Abstract:We propose a new class of waveform foundation models that departs from conventional sequence based representations by modeling physiological time series as realizations of latent event processes. Rather than treating signals as collections of local tokens or patches, our approach assumes that clinically meaningful structure arises from temporally extended, interacting events whose boundaries and dynamics are not directly observed. To capture this structure, we introduce a self supervised learning framework that enforces consistency across stochastic segmentations and time frequency projections of the same waveform, encouraging representations that are invariant to signal level perturbations while preserving event level organization. The resulting model combines a segmentation aware encoder with a latent interaction operator that captures dependencies among inferred events, and naturally extends to multimodal settings by aligning modalities through shared event representations. Across a range of physiological benchmarks, including arrhythmia classification, hemodynamic prediction, and waveform retrieval, the proposed method improves performance, robustness, and label efficiency relative to strong sequence based baselines. These results suggest that shifting from signal centric to event centric representations provides a more appropriate inductive bias for modeling physiological dynamics and offers a complementary path to scaling foundation models in healthcare.
| Subjects: | Machine Learning (cs.LG); Artificial Intelligence (cs.AI) |
| Cite as: | arXiv:2605.08685 [cs.LG] |
| (or arXiv:2605.08685v1 [cs.LG] for this version) | |
| https://doi.org/10.48550/arXiv.2605.08685 arXiv-issued DOI via DataCite (pending registration) |
Submission history
From: Shi Li [view email]
[v1]
Sat, 9 May 2026 04:49:56 UTC (1,719 KB)