Spain’s AI ecosystem entered 2026 on the back of a breakout year that cemented the country’s position as one of Europe’s fastest-growing innovation hubs.
Spanish startups raised €3.1 billion in venture capital funding in 2025, with AI emerging as the nation’s most-funded sector, attracting €717 million in investment, according to Dealroom data. The same report shows that Spain’s AI ecosystem has secured €3.3 billion in funding since 2020, making it the sixth-largest AI market in Europe by investment volume.
Major funding rounds from companies such as TravelPerk and Multiverse Computing helped place Spain firmly on the global AI map in 2025. Momentum has carried into 2026, with investors continuing to back Spanish AI startups across sectors including healthcare, industrial software, geospatial intelligence, and enterprise automation.
Here are the companies leading the charge, ranked from highest to lowest total funding.
Job&Talent
Founders: Juan Urdiales, Felipe Navío
Founded year: 2009
Total funding: $1.2B
Madrid-based Job&Talent has evolved from a staffing marketplace into one of Europe’s largest AI-driven workforce platforms. The company uses machine learning to automate hiring, workforce scheduling, payroll management, and productivity tracking for logistics, retail, and warehouse operators globally. Its platform matches temporary workers with employers in real time while optimising staffing demand through predictive analytics.
The company raised €103 million from Atomico, Kinnevik, BlackRock, SoftBank Vision Fund, and DN Capital in its Series F round in April 2025 to expand internationally and strengthen its AI automation tools for large employers.
Job&Talent counts SoftBank and Goldman Sachs among its longer-standing backers and has a total valuation of $1.2 billion, making it the highest-valued unicorn in Spain.
Xoople
Founders: Fabrizio Pirondini, Álvaro Coronado Cid
Founded year: 2020
Total funding: $280M
Xoople, based in Madrid, is building one of Europe’s most ambitious geospatial AI platforms. The startup combines satellite imagery, machine learning, and earth observation technologies to create dynamic digital twins of the planet. Governments, insurers, urban planners, and infrastructure operators use its data to monitor environmental and industrial changes in near real time.
Xoople secured $130 million from Nazca Capital, which led the round, alongside MCH Private Equity, Buenavista Equity Partners, and Endeavor to scale satellite capabilities and expand its AI imaging platform globally.
The company also announced a partnership with US defence contractor L3Harris Technologies to design and manufacture sensors for its own satellite constellation.
Biorce
Founders: Clara Bernardes, Pedro Coelho, José Faria, Diogo Pisoeiro
Founded year: 2024
Total funding: $61.4M
Barcelona-based Biorce uses artificial intelligence to streamline clinical trial design and drug development workflows. Its platform helps pharmaceutical companies predict patient recruitment challenges, optimise trial protocols, and reduce delays that typically cost the industry billions.
Earlier this year, Biorce raised $52 million, about €44 million, to expand across Europe and the US and to strengthen partnerships with pharmaceutical firms. The investment came from DST Global, Norrsken VC, Mustard Seed MAZE, YZR Capital, and Arthur Mensch, co-founder and CEO at Mistral AI.
Fracttal
Founders: Christian Struve, Alejandro Pérez
Founded year: 2015
Total funding: $50.5M
Headquartered in Madrid, Fracttal develops AI predictive maintenance software for industrial companies. Its platform analyses operational data from machinery and connected devices to forecast equipment failures before they happen, helping manufacturers reduce downtime and maintenance costs.
The company secured $35 million, approximately €30 million, to improve its predictive analytics technology and expand internationally. It was led by Riverwood Capital, with participation from all existing investors, including Seaya Ventures, Kayyak, GoHub, and Amador.
Universal Diagnostics
Founders: Juan Martínez-Barea, Marko Bitenc
Founded year: 2012
Total funding: $158M
Universal Diagnostics is focused on AI-assisted early cancer detection through blood-based diagnostics. The company combines machine learning with genomic and epigenetic analysis to identify cancer biomarkers at very early stages, particularly for colorectal cancer.
Its €30 million funding in January came from the Government of Spain to support commercialisation and regulatory expansion across Europe.
Tucuvi
Founders: María González Veracruz, Marcos Rubio Rubio
Founded year: 2019
Total funding: $22.9M
Tucuvi develops conversational AI tools for healthcare providers. Its voice-based virtual assistant enables hospitals and clinics to monitor patients remotely, automate follow-ups, and reduce pressure on medical staff.
In January 2026, the startup raised €17 million from Seaya, Frontline Ventures, and Cathay Innovation to expand into new healthcare systems and improve multilingual AI voice tools.
Sherpa AI
Founder: Xabi Uribe-Etxebarria
Founded year: 2012
Total funding: $47.6M
Sherpa AI has long been one of Spain’s best-known artificial intelligence companies, specialising in federated learning and privacy-preserving AI systems. Its technology allows organisations to train AI models collaboratively without sharing sensitive underlying data.
Last month, the company secured €11 million in 2026 to expand deployments across banking, healthcare, telecom, and government sectors.
Optimitive
Founders: Javier A. García Sedano
Founded year: 2008
Total funding: $17.4M
Founded by a physicist-turned-AI entrepreneur, Optimitive builds industrial AI software focused on process optimisation for sectors including cement, mining, metals, and heavy manufacturing. Its technology analyses plant operations in real time to improve productivity while reducing energy consumption and emissions.
The startup raised €5 million from Suma Capital, CEMEX Ventures and others to expand internationally and scale its optimisation technology.
Lang AI
Founders: Jorge Peñalva Zambrano, Enrique Fueyo Ramírez
Founded year: 2012
Total funding: $14.5M
Lang AI, a B2B startup founded in Madrid, offers a no-code service-automation platform that empowers customer support teams to visually build AI models and automation logic on top of existing platforms such as Zendesk or Salesforce.
Earlier this year, Capacity, used by more than 20,000 companies, acquired Lang.ai to strengthen its customer support automation capabilities.
Delfos Energy
Founders: Guilherme Studart, Samuel Lima
Founded year: 2017
Total funding: $11.1M
Delfos Energy is a Barcelona-based AI company building “virtual engineer” technology for the energy industry. The company develops applied AI solutions for renewable energy and energy infrastructure operators, helping them manage assets more efficiently, reliably, and at scale. Its platform functions as a constantly operating virtual engineer, ingesting operational data in real time, detecting abnormal behaviour and early-stage failures, interpreting complex signals in context, and converting them into prioritised action recommendations.
In March, the company secured a €3 million seed extension round, including investment from Vox Capital. Existing investors also joined, including Headline, Contrarian Ventures, DOMO VC, and EDP Ventures.